Pregnan­cy

It is pos­si­ble to have a baby whilst having lupus.

Whe­re­as doc­tors used to advi­se against pregnan­cy in peo­p­le with lupus, lupus is no lon­ger a bar­ri­er to having a baby. Anyo­ne with lupus plan­ning a pregnan­cy should defi­ni­te­ly dis­cuss this with their doc­tor, as tre­at­ment will need to be adjusted. 

From a medi­cal point of view, the­re is no rea­son why a woman should not beco­me pregnant pro­vi­ded that her dise­a­se acti­vi­ty has been low for at least 4–6 months pri­or to plan­ned con­cep­ti­on and the­re is no serious organ dama­ge. If lupus is sta­ble and dor­mant at the time of con­cep­ti­on, the risks of dise­a­se fla­res and pregnan­cy com­pli­ca­ti­ons are signi­fi­cant­ly lower than when dise­a­se acti­vi­ty is high. 

Poten­ti­al risks

Pregnan­cy in women with lupus is con­side­red a high-risk pregnancy. 

The­re are cer­tain risks for both the mother and the baby. Pregnant women expe­ri­ence a hig­her than avera­ge num­ber of fla­re-ups and epi­so­des of lupus acti­vi­ty. Com­pli­ca­ti­ons are also more com­mon, such as car­dio­vas­cu­lar pro­blems (pre-eclamp­sia, high blood pres­su­re, throm­bo­sis, inflamma­ti­on of the heart mus­cle or the peri­car­di­um). For the foe­tus and embryo, the­re is a hig­her risk of mis­car­ria­ge, growth retar­da­ti­on and pre­ma­tu­re birth. 

To mini­mi­se the risks, it is important to plan a pregnan­cy careful­ly and at an ear­ly stage. It is recom­men­ded that you attend a con­sul­ta­ti­on at a spe­cia­list cli­nic as soon as you start thin­king about having a baby. 

During pregnan­cy

As a gene­ral rule, medi­cal check-ups and ante­na­tal care must be tail­o­red to the indi­vi­du­al risk pro­fi­le of tho­se affec­ted by lupus.

As this is a high-risk pregnan­cy, women with lupus under­go more fre­quent ante­na­tal check-ups than tho­se wit­hout the con­di­ti­on. Lupus acti­vi­ty should be moni­to­red every 4–6 weeks, par­ti­cu­lar­ly during the second half of the pregnancy. 

It is often neces­sa­ry to switch to pregnan­cy-safe medi­ca­ti­on befo­re con­cep­ti­on. Howe­ver, it is by no means advi­sa­ble to stop taking all medi­ca­ti­on befo­re a plan­ned pregnancy. 

After pregnan­cy

It is important for peo­p­le with lupus to be well infor­med and to be cared for by a mul­ti­di­sci­pli­na­ry team of specialists.

Lupus acti­vi­ty often increa­ses fol­lo­wing pregnan­cy. For this rea­son, doc­tors usual­ly moni­tor lupus pati­ents more clo­se­ly after the birth of their child. 

Fur­ther information

Fur­ther infor­ma­ti­on: You can find fur­ther details via the links to Insel­spi­tal Bern and Rheu­ma­to­lo­gy & Immunology.

The Lupus Suis­se maga­zi­ne artic­le on ‘The desi­re to have child­ren among women with lupus’ is well worth a read!